Bb P 0.001. MDA, malondialdehyde; SOD, superoxide dismutase; 3-NT, 3-nitrotyrosine.enzymes, which promotes protective adaptations [124]. The upregulation of antioxidant defenses in animal models of T2DM was also observed by Nishida et al. [104], which also reported increased Cu/Zn-SOD protein production as a benefits of low-intensity exercise, in contrast with increased Mn-SOD just after moderate